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Striatal Infusion of Glial Conditioned Medium Diminishes Huntingtin Pathology in R6/1 Mice

Huntington's disease is a neurodegenerative disorder caused by an expansion of CAG repeats in the huntingtin gene which produces widespread neuronal and glial pathology. We here investigated the possible therapeutic role of glia or glial products in Huntington's disease using striatal glia...

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Bibliografiske detaljer
Main Authors: Perucho, Juan, Casarejos, Maria José, Gómez, Ana, Ruíz, Carolina, Fernández-Estevez, Maria Ángeles, Muñoz, Maria Paz, de Yébenes, Justo García, Mena, Maria Ángeles
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771920/
https://ncbi.nlm.nih.gov/pubmed/24069174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073120
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