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Synergistic effect of hydrogen peroxide on polyploidization during the megakaryocytic differentiation of K562 leukemia cells by PMA

The human myelogenous cell line, K562 has been extensively used as a model for the study of megakaryocytic (MK) differentiation, which could be achieved by exposure to phorbol 12-myristate 13-acetate (PMA). In this study, real-time PCR analysis revealed that the expression of catalase (cat) was sign...

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Autors principals: Ojima, Yoshihiro, Duncan, Mark Thompson, Nurhayati, Retno Wahyu, Taya, Masahito, Miller, William Martin
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3771872/
https://ncbi.nlm.nih.gov/pubmed/23770036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2013.06.002
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