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Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammation
The pregnane X receptor (PXR) and constitutive androstane receptor (CAR) have been known to play a role in xenobiotic metabolism by regulating the expression of drug-metabolizing enzymes and transporters. In addition, PXR agonists were found to exert therapeutic effects through multiple mechanisms,...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3771640/ https://ncbi.nlm.nih.gov/pubmed/23896737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1101-9 |
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