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Genetic Manipulations of Mutant Huntingtin in Mice: New Insights into HD Pathogenesis

This year (2013) marks the twentieth anniversary of the identification of the causal genetic mutation for Huntington’s disease (HD), a landmark discovery that has heralded the study of the biological underpinnings of this most common dominantly inherited neurodegenerative disorder. Among the variety...

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Detalhes bibliográficos
Main Authors: Lee, C.Y. Daniel, Cantle, Jeffrey P., Yang, X. William
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770892/
https://ncbi.nlm.nih.gov/pubmed/23829302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12418
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