Probability Distribution of Drug-Resistant Mutants in Unselected Populations of Mycobacterium tuberculosis
The fluctuation test shows that Mycobacterium tuberculosis mutates to resistance to isoniazid, streptomycin, ethambutol and rifampin spontaneously and at random. The average mutation rates for the drugs, in the same order, were calculated to be 2.56 × 10(−8), 2.95 × 10(−8), 10(−7), and 2.25 × 10(−10...
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| Publicado en: | Appl Microbiol |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1970
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| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC377053/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4991927/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/am.20.5.810-814.1970 |
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