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Probability Distribution of Drug-Resistant Mutants in Unselected Populations of Mycobacterium tuberculosis

The fluctuation test shows that Mycobacterium tuberculosis mutates to resistance to isoniazid, streptomycin, ethambutol and rifampin spontaneously and at random. The average mutation rates for the drugs, in the same order, were calculated to be 2.56 × 10(−8), 2.95 × 10(−8), 10(−7), and 2.25 × 10(−10...

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Bibliografske podrobnosti
izdano v:Appl Microbiol
Glavni avtor: David, Hugo L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1970
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC377053/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4991927/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/am.20.5.810-814.1970
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