Characterization of the colorectal cancer–associated enhancer MYC-335 at 8q24: the role of rs67491583

Recent genome-wide association studies have identified multiple regions at 8q24 that confer susceptibility to many cancers. In our previous work, we showed that the colorectal cancer (CRC) risk variant rs6983267 at 8q24 resides within a TCF4 binding site at the MYC-335 enhancer, with the risk allele...

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Main Authors: Tuupanen, Sari, Yan, Jian, Turunen, Mikko, Gylfe, Alexandra E., Kaasinen, Eevi, Li, Li, Eng, Charis, Culver, Daniel A., Kalady, Matthew F., Pennison, Michael J., Pasche, Boris, Manne, Upender, de la Chapelle, Albert, Hampel, Heather, Henderson, Brian E., Marchand, Loic Le, Hautaniemi, Sampsa, Askhtorab, Hassan, Smoot, Duane, Sandler, Robert S., Keku, Temitope, Kupfer, Sonia S., Ellis, Nathan A., Haiman, Christopher A., Taipale, Jussi, Aaltonen, Lauri A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770308/
https://ncbi.nlm.nih.gov/pubmed/22429595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2012.01.005
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