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Flexible Analytical methods for Adding a Treatment Arm Mid-study to an Ongoing Clinical Trial

It is not uncommon to have experimental drugs under different stages of development for a given disease area. Methods are proposed for use when another treatment arm is to be added mid-study to an ongoing clinical trial. Monte Carlo simulation was used to compare potential analytical approaches for...

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Detalhes bibliográficos
Main Authors: Elm, Jordan J., Palesch, Yuko Y., Koch, Gary G., Hinson, Vanessa, Ravina, Bernard, Zhao, Wenle
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770292/
https://ncbi.nlm.nih.gov/pubmed/22651113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2010.528103
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