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Statistical consideration when adding new arms to ongoing clinical trials: the potentials and the caveats

BACKGROUND: Platform trials improve the efficiency of the drug development process through flexible features such as adding and dropping arms as evidence emerges. The benefits and practical challenges of implementing novel trial designs have been discussed widely in the literature, yet less consider...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Lee, Kim May, Brown, Louise C., Jaki, Thomas, Stallard, Nigel, Wason, James
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944243/
https://ncbi.nlm.nih.gov/pubmed/33691748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-021-05150-7
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