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Statistical consideration when adding new arms to ongoing clinical trials: the potentials and the caveats

BACKGROUND: Platform trials improve the efficiency of the drug development process through flexible features such as adding and dropping arms as evidence emerges. The benefits and practical challenges of implementing novel trial designs have been discussed widely in the literature, yet less consider...

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Bibliografiska uppgifter
I publikationen:Trials
Huvudupphovsmän: Lee, Kim May, Brown, Louise C., Jaki, Thomas, Stallard, Nigel, Wason, James
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944243/
https://ncbi.nlm.nih.gov/pubmed/33691748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-021-05150-7
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