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Probing lipid-protein adduction with alkynyl surrogates: application to Smith-Lemli-Opitz syndrome

Lipid modifications aid in regulating (and misregulating) protein function and localization. However, efficient methods to screen for a lipid's ability to modify proteins are not readily available. We present a strategy to identify protein-reactive lipids and apply it to a neurodevelopmental di...

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Detalhes bibliográficos
Main Authors: Windsor, Katherine, Genaro-Mattos, Thiago C., Kim, Hye-Young H., Liu, Wei, Tallman, Keri A., Miyamoto, Sayuri, Korade, Zeljka, Porter, Ned A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770096/
https://ncbi.nlm.nih.gov/pubmed/23828810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M041061
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