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MD simulations suggest important surface differences between reconstituted and circulating spherical HDL(1)

Since spheroidal HDL particles (sHDL) are highly dynamic, molecular dynamics (MD) simulations are useful for obtaining structural models. Here we use MD to simulate sHDL with stoichiometries of reconstituted and circulating particles. The hydrophobic effect during simulations rapidly remodels discoi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Segrest, Jere P., Jones, Martin K., Catte, Andrea
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770085/
https://ncbi.nlm.nih.gov/pubmed/23856070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M039206
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