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Validation of previous computer models and MD simulations of discoidal HDL by a recent crystal structure of apoA-I

HDL is a population of apoA-I-containing particles inversely correlated with heart disease. Because HDL is a soft form of matter deformable by thermal fluctuations, structure determination has been difficult. Here, we compare the recently published crystal structure of lipid-free (Δ185-243)apoA-I wi...

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Detalhes bibliográficos
Main Authors: Segrest, Jere P., Jones, Martin K., Catte, Andrea, Thirumuruganandham, Saravana P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413226/
https://ncbi.nlm.nih.gov/pubmed/22773698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M026229
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