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Direct, Enantioselective Synthesis of Pyrroloindolines and Indolines From Simple Indole Derivatives

The (R)-BINOL•SnCl(4)-catalyzed formal (3 + 2) cycloaddition between 3-substituted indoles and benzyl 2-trifluoroacetamidoacrylate is a direct, enantioselective method to prepare pyrroloindolines from simple starting materials. However, under the originally disclosed conditions, the pyrroloindolines...

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Bibliographic Details
Main Authors: Ni, Jane, Wang, Haoxuan, Reisman, Sarah E.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769991/
https://ncbi.nlm.nih.gov/pubmed/24039305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2013.04.003
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