SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways

Protein function is regulated by diverse posttranslational modifications. The mitochondrial sirtuin SIRT5 removes malonyl and succinyl moieties from target lysines. The spectrum of protein substrates subject to these modifications is unknown. We report systematic profiling of the mammalian succinylo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Park, Jeongsoon, Chen, Yue, Tishkoff, Daniel X., Peng, Chao, Tan, Minjia, Dai, Lunzhai, Xie, Zhongyu, Zhang, Yi, Zwaans, Bernadette M.M., Skinner, Mary E., Lombard, David B., Zhao, Yingming
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769971/
https://ncbi.nlm.nih.gov/pubmed/23806337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.06.001
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge