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DrGaP: A Powerful Tool for Identifying Driver Genes and Pathways in Cancer Sequencing Studies
Cancers are caused by the accumulation of genomic alterations. Driver mutations are required for the cancer phenotype, whereas passenger mutations are irrelevant to tumor development and accumulate through DNA replication. A major challenge facing the field of cancer genome sequencing is to identify...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769934/ https://ncbi.nlm.nih.gov/pubmed/23954162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.07.003 |
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