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DrGaP: A Powerful Tool for Identifying Driver Genes and Pathways in Cancer Sequencing Studies
Cancers are caused by the accumulation of genomic alterations. Driver mutations are required for the cancer phenotype, whereas passenger mutations are irrelevant to tumor development and accumulate through DNA replication. A major challenge facing the field of cancer genome sequencing is to identify...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769934/ https://ncbi.nlm.nih.gov/pubmed/23954162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.07.003 |
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