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DrGaP: A Powerful Tool for Identifying Driver Genes and Pathways in Cancer Sequencing Studies

Cancers are caused by the accumulation of genomic alterations. Driver mutations are required for the cancer phenotype, whereas passenger mutations are irrelevant to tumor development and accumulate through DNA replication. A major challenge facing the field of cancer genome sequencing is to identify...

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Podrobná bibliografie
Hlavní autoři: Hua, Xing, Xu, Haiming, Yang, Yaning, Zhu, Jun, Liu, Pengyuan, Lu, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769934/
https://ncbi.nlm.nih.gov/pubmed/23954162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.07.003
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