AR Variant AR(v567es) Induces Carcinogenesis in a Novel Transgenic Mouse Model of Prostate Cancer

Androgen deprivation therapy remains the primary treatment modality for patients with metastatic prostate cancer but is uniformly marked by progression to castration-resistant prostate cancer (CRPC) after a period of regression. Continued activation of androgen receptor (AR) signaling is attributed...

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Main Authors: Liu, Gang, Sprenger, Cynthia, Sun, Shihua, Epilepsia, Kathryn Soriano, Haugk, Kathleen, Zhang, Xiaotun, Coleman, Ilsa, Nelson, Peter S, Plymate, Stephen
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press Inc. 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769880/
https://ncbi.nlm.nih.gov/pubmed/24027426
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