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Sensitive, Site-Specific, and Stable Vibrational Probe of Local Protein Environments: 4-Azidomethyl-L-Phenylalanine

We have synthesized the unnatural amino acid (UAA), 4-azidomethyl-Lphenylalanine (pN(3)CH(2)Phe), to serve as an effective vibrational reporter of local protein environments. The position, extinction coefficient, and sensitivity to local environment of the azide asymmetric stretch vibration of pN(3)...

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Detalhes bibliográficos
Main Authors: Bazewicz, Christopher G., Liskov, Melanie T., Hines, Kevin J., Brewer, Scott H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769706/
https://ncbi.nlm.nih.gov/pubmed/23865850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp4052598
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