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A general, enantioselective synthesis of β- and γ-fluoroamines

In this Letter, we describe a short, high yielding protocol for the enantioselective (87–96% ee) and general synthesis of β-fluoroamines and previously difficult to access γ-fluoroamines from commercial aldehydes via organocatalysis.

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Autors principals: O’Reilly, Matthew C., Lindsley, Craig W.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769685/
https://ncbi.nlm.nih.gov/pubmed/24039308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2013.04.116
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