Hydrogen sulfide-releasing aspirin inhibits the growth of leukemic Jurkat cells and modulates β-catenin expression

Hydrogen sulfide-releasing aspirin (HS-ASA) is a novel compound with potential against cancer. It inhibited the growth of Jurkat T-leukemia cells with an IC(50) of 1.9 ± 0.2 µM whereas that of ASA was >5000 µM. It dose-dependently inhibited proliferation and induced apoptosis in these cells, caus...

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Main Authors: Chattopadhyay, Mitali, Nath, Niharika, Kodela, Ravinder, Sobocki, Tomasz, Metkar, Shalaka, Gan, Zong Yuan, Kashfi, Khosrow
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769470/
https://ncbi.nlm.nih.gov/pubmed/23896061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.07.004
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