Determination of dosage compensation of the mammalian X chromosome by RNA-seq is dependent on analytical approach

BACKGROUND: An enduring question surrounding sex chromosome evolution is whether effective hemizygosity in the heterogametic sex leads inevitably to dosage compensation of sex-linked genes, and whether this compensation has been observed in a variety of organisms. Incongruence in the conclusions rea...

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Main Authors: Jue, Nathaniel K, Murphy, Michael B, Kasowitz, Seth D, Qureshi, Sohaib M, Obergfell, Craig J, Elsisi, Sahar, Foley, Robert J, O’Neill, Rachel J, O’Neill, Michael J
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3769146/
https://ncbi.nlm.nih.gov/pubmed/23497106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-150
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