Dosage Compensation and Gene Expression of the X Chromosome in Sheep

Ohno’s hypothesis predicts that the expression of the single X chromosome in males needs compensatory upregulation to balance its dosage with that of the diploid autosomes. Additionally, X chromosome inactivation ensures that quadruple expression of the two X chromosomes is avoided in females. These...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Duan, Jingyue (Ellie), Flock, Kaleigh, Jue, Nathanial, Zhang, Mingyuan, Jones, Amanda, Seesi, Sahar Al, Mandoiu, Ion, Pillai, Sambhu, Hoffman, Maria, O’Neill, Rachel, Zinn, Steven, Govoni, Kristen, Reed, Sarah, Jiang, Hesheng, Jiang, Zongliang (Carl), Tian, Xiuchun (Cindy)
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
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Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325915/
https://ncbi.nlm.nih.gov/pubmed/30482800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200815
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