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Methylome Dynamics of Bovine Gametes and in vivo Early Embryos

DNA methylation undergoes drastic fluctuation during early mammalian embryogenesis. The dynamics of global DNA methylation in bovine embryos, however, have mostly been studied by immunostaining. We adopted the whole genome bisulfite sequencing (WGBS) method to characterize stage-specific genome-wide...

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Bibliografiske detaljer
Udgivet i:Front Genet
Main Authors: Duan, Jingyue Ellie, Jiang, Zongliang Carl, Alqahtani, Fahad, Mandoiu, Ion, Dong, Hong, Zheng, Xinbao, Marjani, Sadie L., Chen, Jingbo, Tian, Xiuchun Cindy
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546829/
https://ncbi.nlm.nih.gov/pubmed/31191619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00512
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