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Cyclophilin D is required for mitochondrial removal by autophagy in cardiac cells

Autophagy is a highly regulated intracellular degradation process by which cells remove cytosolic long-lived proteins and damaged organelles. The mitochondrial permeability transition (MPT) results in mitochondrial depolarization and increased reactive oxygen species production, which can trigger au...

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Bibliographic Details
Main Authors: Carreira, Raquel S., Lee, Youngil, Ghochani, Mariam, Gustafsson, Åsa B., Gottlieb, Roberta A.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3768271/
https://ncbi.nlm.nih.gov/pubmed/20364102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.6.4.11553
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