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Beta Cell 5′-Shifted isomiRs Are Candidate Regulatory Hubs in Type 2 Diabetes

Next-generation deep sequencing of small RNAs has unveiled the complexity of the microRNA (miRNA) transcriptome, which is in large part due to the diversity of miRNA sequence variants (“isomiRs”). Changes to a miRNA’s seed sequence (nucleotides 2–8), including shifted start positions, can redirect t...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Baran-Gale, Jeanette, Fannin, Emily E., Kurtz, C. Lisa, Sethupathy, Praveen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767796/
https://ncbi.nlm.nih.gov/pubmed/24039891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073240
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