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Beta Cell 5′-Shifted isomiRs Are Candidate Regulatory Hubs in Type 2 Diabetes

Next-generation deep sequencing of small RNAs has unveiled the complexity of the microRNA (miRNA) transcriptome, which is in large part due to the diversity of miRNA sequence variants (“isomiRs”). Changes to a miRNA’s seed sequence (nucleotides 2–8), including shifted start positions, can redirect t...

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Bibliografiske detaljer
Main Authors: Baran-Gale, Jeanette, Fannin, Emily E., Kurtz, C. Lisa, Sethupathy, Praveen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767796/
https://ncbi.nlm.nih.gov/pubmed/24039891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073240
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