High-level, lasting antiviral immunity induced by a bimodal AIDS vaccine and boosted by live-virus exposure: prevention of viremia

OBJECTIVE: To characterize the correlates of protection from systemic infection in a vaccinated rhesus macaque (RM), RAt-9, which had been challenged sequentially with two related clade C simian-human immunodeficiency viruses (SHIV-Cs) yet remained aviremic for >5 years despite indirect evidence...

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Hoofdauteurs: RASMUSSEN, Robert A., SIDDAPPA, Nagadenahalli B., LAKHASHE, Samir K., WATKINS, Jennifer, VILLINGER, François, IBEGBU, Chris, FLORESE, Ruth H., ROBERT-GUROFF, Marjorie, MONTEFIORI, David C., FORTHAL, Donald N., O’CONNOR, David, RUPRECHT, Ruth M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767758/
https://ncbi.nlm.nih.gov/pubmed/21941166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32834d3c4f
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