Engineering Customized TALE Nucleases (TALENs) and TALE Transcription Factors by Fast Ligation-based Automatable Solid-phase High-throughput (FLASH) Assembly

Customized DNA-binding domains made using Transcription Activator-Like Effector (TALE) repeats are rapidly growing in importance as widely applicable research tools. TALE nucleases (TALENs), composed of an engineered array of TALE repeats fused to the FokI nuclease domain, have been used successfull...

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Autori principali: Reyon, Deepak, Maeder, Morgan L., Khayter, Cyd, Tsai, Shengdar Q., Foley, Jonathan E., Sander, Jeffry D., Joung, J. Keith
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767754/
https://ncbi.nlm.nih.gov/pubmed/23821439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142727.mb1216s103
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