Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs)

Zinc Finger Nucleases (ZFNs) made by Context-Dependent Assembly (CoDA) and Transcription Activator-Like Effector Nucleases (TALENs) provide robust and user-friendly technologies for efficiently inactivating genes in zebrafish. These designer nucleases bind to and cleave DNA at particular target site...

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Detalhes bibliográficos
Main Authors: Moore, Finola E., Reyon, Deepak, Sander, Jeffry D., Martinez, Sarah A., Blackburn, Jessica S., Khayter, Cyd, Ramirez, Cherie L., Joung, J. Keith, Langenau, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360007/
https://ncbi.nlm.nih.gov/pubmed/22655075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037877
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