SNP Detection in mRNA in Living Cells Using Allele Specific FRET Probes

Live mRNA detection allows real time monitoring of specific transcripts and genetic alterations. The main challenge of live genetic detection is overcoming the high background generated by unbound probes and reaching high level of specificity with minimal off target effects. The use of Fluorescence...

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Bibliographic Details
Main Authors: Dahan, Liya, Huang, Lingyan, Kedmi, Ranit, Behlke, Mark A., Peer, Dan
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767744/
https://ncbi.nlm.nih.gov/pubmed/24039756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072389
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