Neutralization of terminal differentiation in gliomagenesis

An immature state of cellular differentiation—characterized by stem cell–like tendencies and impaired differentiation—is a hallmark of cancer. Using glioblastoma multiforme (GBM) as a model system, we sought to determine whether molecular determinants that drive cells toward terminal differentiation...

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Detalhes bibliográficos
Main Authors: Hu, Jian, Ho, Allen L., Yuan, Liang, Hu, Baoli, Hua, Sujun, Hwang, Soyoon Sarah, Zhang, Jianhua, Hu, Tianyi, Zheng, Hongwu, Gan, Boyi, Wu, Gongxiong, Wang, Yaoqi Alan, Chin, Lynda, DePinho, Ronald A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767545/
https://ncbi.nlm.nih.gov/pubmed/23918370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308610110
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