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A nanoparticle formulation that selectively transfects metastatic tumors in mice

Nanoparticle gene therapy holds great promise for the treatment of malignant disease in light of the large number of potent, tumor-specific therapeutic payloads potentially available for delivery. To be effective, gene therapy vehicles must be able to deliver their therapeutic payloads to metastatic...

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Hlavní autoři: Yang, Jian, Hendricks, William, Liu, Guosheng, McCaffery, J. Michael, Kinzler, Kenneth W., Huso, David L., Vogelstein, Bert, Zhou, Shibin
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767543/
https://ncbi.nlm.nih.gov/pubmed/23959886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1313330110
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