Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors

Tumor endothelial marker 1 (Tem1; endosialin) is the prototypical member of a family of genes expressed in the stroma of tumors. To assess the functional role of Tem1, we disrupted the Tem1 gene in mice by targeted homologous recombination. Tem1(−/−) mice were healthy, their wound healing was normal...

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Bibliographic Details
Main Authors: Nanda, Akash, Karim, Baktiar, Peng, Zhongsheng, Liu, Guosheng, Qiu, Weiping, Gan, Christine, Vogelstein, Bert, St. Croix, Brad, Kinzler, Kenneth W., Huso, David L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1413931/
https://ncbi.nlm.nih.gov/pubmed/16492758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0511306103
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