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DNA Vaccine that Targets Hemagglutinin to MHC Class II Molecules Rapidly Induces Antibody-Mediated Protection against Influenza

New influenza A viruses with pandemic potential periodically emerge due to viral genomic reassortment. In the face of pandemic threats, production of conventional egg-based vaccines is time consuming and of limited capacity. We have developed in this study a novel DNA vaccine in which viral hemagglu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grodeland, Gunnveig, Mjaaland, Siri, Roux, Kenneth H., Fredriksen, Agnete Brunsvik, Bogen, Bjarne
Format: Artigo
Sprache:Inglês
Veröffentlicht: AAI 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767367/
https://ncbi.nlm.nih.gov/pubmed/23956431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300504
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