Iterative experimental and virtual high-throughput screening identifies metabotropic glutamate receptor subtype 4 positive allosteric modulators

Lignende værker

• Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening
  af: Mueller, Ralf, et al.
  Udgivet: (2010)
• Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors
  af: Lindsley, Craig W., et al.
  Udgivet: (2016)
• Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-lead
  af: Williams, Richard, et al.
  Udgivet: (2008)
• Synthesis and SAR of a Novel Positive Allosteric Modulator (PAM) of the Metabotropic Glutamate Receptor 4 (mGluR4)
  af: Williams, Richard, et al.
  Udgivet: (2009)
• Identification of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Acting at Site Distinct from 2-Methyl-6-(phenylethynyl)-pyridine Binding
  af: Butkiewicz, Mariusz, et al.
  Udgivet: (2019)