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Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening
[Image: see text] Selective potentiators of glutamate response at metabotropic glutamate receptor subtype 5 (mGluR5) have exciting potential for the development of novel treatment strategies for schizophrenia. A total of 1,382 compounds with positive allosteric modulation (PAM) of the mGluR5 glutama...
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| Hauptverfasser: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical Society
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857954/ https://ncbi.nlm.nih.gov/pubmed/20414370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn9000389 |
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