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Bevacizumab-Based Treatment in Colorectal Cancer with a NRAS Q61K Mutation

Despite development of new therapies, metastatic colorectal cancer (mCRC) largely remains an incurable disease. Approximately 2–6% of colorectal cancers harbor NRAS mutations. The anti-VEGF antibody bevacizumab is a backbone of most therapeutic regimens; however, biomarkers predicting its activity a...

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Detaylı Bibliyografya
Asıl Yazarlar: Janku, Filip, Wheler, Jennifer J., Hong, David S., Kurzrock, Razelle
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766504/
https://ncbi.nlm.nih.gov/pubmed/23400451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-013-0266-9
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