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Structural basis for regulation of Arp2/3 complex by GMF

Arp2/3 complex mediates formation of complex cellular structures such as lamellapodia by nucleating branched actin filaments. Arp2/3 complex activity is precisely controlled by more than a dozen regulators, yet the structural mechanism by which regulators interact with the complex is unknown. GMF is...

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Detalhes bibliográficos
Main Authors: Luan, Qing, Nolen, Brad J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766443/
https://ncbi.nlm.nih.gov/pubmed/23893131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2628
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