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Design of inhibitors using a combinatorial library for HIV-Nef and human SH3 domain interaction
The HIV-1 Nef protein has the ability to down regulate important molecules at the immune synapse. These include class I and class II (Human Leukocyte Antigen) HLA on the Antigen Presenting Cells (APC). The receptors in these molecules consist of SH-3 domain and their interaction with the HIV-1 Nef i...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Biomedical Informatics
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3766310/ https://ncbi.nlm.nih.gov/pubmed/24023420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630009777 |
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