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Design of inhibitors using a combinatorial library for HIV-Nef and human SH3 domain interaction

The HIV-1 Nef protein has the ability to down regulate important molecules at the immune synapse. These include class I and class II (Human Leukocyte Antigen) HLA on the Antigen Presenting Cells (APC). The receptors in these molecules consist of SH-3 domain and their interaction with the HIV-1 Nef i...

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Autori principali: Kakkar, Jatin, Chaudhary, Kamal Kumar, Prasad, Chekkara Venkata Satya Siva
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biomedical Informatics 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766310/
https://ncbi.nlm.nih.gov/pubmed/24023420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630009777
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