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Defining SH2 domain and PTP specificity by screening combinatorial peptide libraries
Src homology 2 (SH2) domains mediate protein-protein interactions by recognizing short phosphotyrosyl (pY) peptide motifs in their partner proteins. Protein tyrosine phosphatases (PTPs) catalyze the dephosphorylation of pY proteins, counteracting the protein tyrosine kinases. Both types of proteins...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2041848/ https://ncbi.nlm.nih.gov/pubmed/17532507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2007.02.010 |
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