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Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo

Neurons and other cells require intracellular transport of essential components for viability and function. Previous work has shown that while net amyloid precursor protein (APP) transport is generally anterograde, individual vesicles containing APP move bi-directionally. This discrepancy highlights...

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Detalhes bibliográficos
Main Authors: Gunawardena, Shermali, Yang, Ge, Goldstein, Lawrence S.B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766177/
https://ncbi.nlm.nih.gov/pubmed/23710041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt237
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