Carregant...

Kinesin-1 transport reductions enhance human tau hyperphosphorylation, aggregation and neurodegeneration in animal models of tauopathies

Neurodegeneration induced by abnormal hyperphosphorylation and aggregation of the microtubule-associated protein tau defines neurodegenerative tauopathies. Destabilization of microtubules by loss of tau function and filament formation by toxic gain of function are two mechanisms suggested for how ab...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Falzone, Tomás L., Gunawardena, Shermali, McCleary, David, Reis, Gerald F., Goldstein, Lawrence S.B.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957317/
https://ncbi.nlm.nih.gov/pubmed/20817925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq363
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!