Nitric oxide modulates the hyperalgesic response to mechanical noxious stimuli in sleep-deprived rats

BACKGROUND: Sleep restriction alters pain perception in animals and humans, and many studies have indicated that paradoxical sleep deprivation (PSD) promotes hyperalgesia. The hyperalgesia observed after mechanical nociceptive stimulus is reversed through nitric oxide synthase (NOS) inhibition. Both...

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Autors principals: Damasceno, Fabio, Skinner, Gabriela O, Araújo, Paulo C, Ferraz, Marcia MD, Tenório, Frank, de Almeida, Olga MMS
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765713/
https://ncbi.nlm.nih.gov/pubmed/23987566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-92
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