Nitric oxide modulates the hyperalgesic response to mechanical noxious stimuli in sleep-deprived rats

BACKGROUND: Sleep restriction alters pain perception in animals and humans, and many studies have indicated that paradoxical sleep deprivation (PSD) promotes hyperalgesia. The hyperalgesia observed after mechanical nociceptive stimulus is reversed through nitric oxide synthase (NOS) inhibition. Both...

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Bibliografiska uppgifter
Huvudupphovsmän: Damasceno, Fabio, Skinner, Gabriela O, Araújo, Paulo C, Ferraz, Marcia MD, Tenório, Frank, de Almeida, Olga MMS
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3765713/
https://ncbi.nlm.nih.gov/pubmed/23987566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-92
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