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Engineering Yeast Hexokinase 2 for Improved Tolerance Toward Xylose-Induced Inactivation
Hexokinase 2 (Hxk2p) from Saccharomyces cerevisiae is a bi-functional enzyme being both a catalyst and an important regulator in the glucose repression signal. In the presence of xylose Hxk2p is irreversibly inactivated through an autophosphorylation mechanism, affecting all functions. Consequently,...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3765440/ https://ncbi.nlm.nih.gov/pubmed/24040384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075055 |
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