Crystal Structure of 3-Hydroxybenzoate 6-Hydroxylase Uncovers Lipid-assisted Flavoprotein Strategy for Regioselective Aromatic Hydroxylation

3-Hydroxybenzoate 6-hydroxylase (3HB6H) from Rhodococcus jostii RHA1 is a dimeric flavoprotein that catalyzes the NADH- and oxygen-dependent para-hydroxylation of 3-hydroxybenzoate to 2,5-dihydroxybenzoate. In this study, we report the crystal structure of 3HB6H as expressed in Escherichia coli. The...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Montersino, Stefania, Orru, Roberto, Barendregt, Arjan, Westphal, Adrie H., van Duijn, Esther, Mattevi, Andrea, van Berkel, Willem J. H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Enzymology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3764827/
https://ncbi.nlm.nih.gov/pubmed/23864660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.479303
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares