Pyridine Nucleotide Coenzyme Specificity of p-Hydroxybenzoate Hydroxylase and Related Flavoprotein Monooxygenases

p-Hydroxybenzoate hydroxylase (PHBH; EC 1.14.13.2) is a microbial group A flavoprotein monooxygenase that catalyzes the ortho-hydroxylation of 4-hydroxybenzoate to 3,4-dihydroxybenzoate with the stoichiometric consumption of NAD(P)H and oxygen. PHBH and related enzymes lack a canonical NAD(P)H-bindi...

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Publicat a:Front Microbiol
Autors principals: Westphal, Adrie H., Tischler, Dirk, Heinke, Florian, Hofmann, Sarah, Gröning, Janosch A. D., Labudde, Dirk, van Berkel, Willem J. H.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315137/
https://ncbi.nlm.nih.gov/pubmed/30631308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.03050
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